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motifcounter

This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

This package is for version 3.23 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see motifcounter.

All versions 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5

R package for analysing TFBSs in DNA sequences


Bioconductor version: Release (3.23)

'motifcounter' provides motif matching, motif counting and motif enrichment functionality based on position frequency matrices. The main features of the packages include the utilization of higher-order background models and accounting for self-overlapping motif matches when determining motif enrichment. The background model allows to capture dinucleotide (or higher-order nucleotide) composition adequately which may reduced model biases and misleading results compared to using simple GC background models. When conducting a motif enrichment analysis based on the motif match count, the package relies on a compound Poisson distribution or alternatively a combinatorial model. These distribution account for self-overlapping motif structures as exemplified by repeat-like or palindromic motifs, and allow to determine the p-value and fold-enrichment for a set of observed motif matches.

Author: Wolfgang Kopp [aut, cre]

Maintainer: Wolfgang Kopp <wolfgang.kopp at mdc-berlin.de>

Citation (from within R, enter citation("motifcounter")):

Wolfgang Kopp. motifcounter: R package for analysing TFBSs in DNA sequences. doi:10.18129/B9.bioc.motifcounter, R package version 1.35.0, https://bioconductor.org/packages/motifcounter.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("motifcounter")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("motifcounter")
Introduction to the `motifcounter` package HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews MotifAnnotation, SequenceMatching, Software, Transcription
Version1.35.0
In Bioconductor sinceBioC 3.5 (R-3.4) (9.5 years)
License GPL-2
Depends R (>= 3.0)
Imports Biostrings, methods
System Requirements
URL
See More
Suggests knitr, rmarkdown, testthat, MotifDb, seqLogo, prettydoc
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package motifcounter_1.35.0.tar.gz
Windows Binary (x86_64) motifcounter_1.35.0.zip (64-bit only)
macOS Binary (big-sur-x86_64)
macOS Binary (sonoma-arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/motifcounter
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/motifcounter
Package Short Url https://bioconductor.org/packages/motifcounter/
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