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CellMentor

This is the released version of CellMentor; for the devel version, see CellMentor.

All versions 3.24 (devel), 3.23 (release)

Supervised Non-negative Matrix Factorization for Dimensional Reduction in Single-Cell Analysis


Bioconductor version: Release (3.23)

Implements supervised cell type-aware non-negative matrix factorization (NMF) for dimensional reduction in single-cell RNA sequencing analysis. The package provides methods for incorporating cell type information into the dimensionality reduction process, enabling improved visualization and downstream analysis of single-cell data while preserving biological structure. CellMentor employs a unique loss function that simultaneously minimizes variation within known cell populations while maximizing distinctions between different cell types, enabling effective transfer of learned patterns from labeled reference datasets to new unlabeled data.

Author: Ekaterina Petrenko [aut, cre] ORCID iD ORCID: 0000-0003-3549-834X

Maintainer: Ekaterina Petrenko <petrenko.kate at icloud.com>

Citation (from within R, enter citation("CellMentor")):

Ekaterina Petrenko. CellMentor: Supervised Non-negative Matrix Factorization for Dimensional Reduction in Single-Cell Analysis. doi:10.18129/B9.bioc.CellMentor, R package version 1.0.1, https://bioconductor.org/packages/CellMentor.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CellMentor")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CellMentor")
Introduction to CellMentor HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DimensionReduction, SingleCell, Software, Transcriptomics
Version1.0.1
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License Apache License (>= 2)
Depends R (>= 4.5.0)
Imports methods, Matrix, BiocParallel, SingleR, Seurat (>= 4.0.0), utils, stats, parallel, progress, ggplot2, data.table, magrittr, graphics, RMTstat, sparsesvd, cluster, skmeans, MLmetrics, tibble, lsa, nnls, SingleCellExperiment, entropy, irlba, aricode
System Requirements
URLhttps://github.com/petrenkokate/CellMentor
Bug Reportshttps://github.com/petrenkokate/CellMentor/issues
See More
Suggests testthat (>= 3.0.0), covr, withr, rmarkdown, knitr, BiocStyle, scater, scRNAseq
Linking To
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Depends On Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CellMentor_1.0.1.tar.gz
Windows Binary (x86_64) CellMentor_1.0.1.zip
macOS Binary (big-sur-x86_64) CellMentor_1.0.1.tgz
macOS Binary (sonoma-arm64) CellMentor_1.0.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CellMentor
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CellMentor
Package Short Url https://bioconductor.org/packages/CellMentor/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive