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BatchQC

This is the released version of BatchQC; for the devel version, see BatchQC.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3

Batch Effects Quality Control Software


Bioconductor version: Release (3.23)

Samples (-omics, imaging, single cell, etc) often are collected or processed in multiple batches or at different times. This often produces technical biases that can lead to incorrect results in the downstream analysis. BatchQC is a software tool that streamlines batch preprocessing and evaluation by providing interactive diagnostics, visualizations, and statistical analyses to explore the extent to which batch variation impacts the data. BatchQC diagnostics help determine whether batch adjustment needs to be done, and how correction should be applied before proceeding with a downstream analysis. Moreover, BatchQC interactively applies multiple common batch effect approaches to the data and the user can quickly see the benefits of each method. BatchQC is developed as a Shiny App. The output is organized into multiple tabs and each tab features an important part of the batch effect analysis and visualization of the data. The BatchQC interface has the following analysis groups: Summary, Differential Expression, Median Correlations, Heatmaps, Circular Dendrogram, PCA Analysis, Shape, ComBat and SVA.

Author: Jessica Anderson [aut] ORCID iD ORCID: 0000-0002-0542-9872 , W. Evan Johnson [aut, fnd] ORCID iD ORCID: 0000-0002-6247-6595 , Yaoan Leng [ctb, cre] ORCID iD ORCID: 0009-0002-3957-5250 , Solaiappan Manimaran [aut], Heather Selby [ctb], Claire Ruberman [ctb], Kwame Okrah [ctb], Hector Corrada Bravo [ctb], Michael Silverstein [ctb], Regan Conrad [ctb], Zhaorong Li [ctb], Evan Holmes [ctb], Solomon Joseph [ctb], Howard Fan [ctb], Sean Lu [ctb]

Maintainer: Yaoan Leng <leng at bu.edu>

Citation (from within R, enter citation("BatchQC")):

Jessica Anderson, W. Evan Johnson, Solaiappan Manimaran. BatchQC: Batch Effects Quality Control Software. doi:10.18129/B9.bioc.BatchQC, R package version 2.8.3, https://bioconductor.org/packages/BatchQC.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("BatchQC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BatchQC")
BatchQC Examples HTML R Script
Introdution to BatchQC HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews BatchEffect, DifferentialExpression, GeneExpression, GraphAndNetwork, ImmunoOncology, Microarray, Normalization, Preprocessing, PrincipalComponent, QualityControl, RNASeq, Sequencing, ShinyApps, Software, Visualization
Version2.8.3
In Bioconductor sinceBioC 3.3 (R-3.3) (10.5 years)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports data.table, DESeq2, dplyr, EBSeq, edgeR, FNN, ggdendro, ggnewscale, ggplot2, ggpubr, Harman, limma, matrixStats, methods, MASS, pheatmap, RColorBrewer, reader, reshape2, scran, shiny, shinyjs, shinythemes, stats, SummarizedExperiment, sva, S4Vectors, tibble, tidyr, tidyverse, umap, utils
System Requirements
URLhttps://github.com/wejlab/BatchQC
Bug Reportshttps://github.com/wejlab/BatchQC/issues
See More
Suggests BiocManager, BiocStyle, bladderbatch, curatedTBData, devtools, knitr, lintr, MultiAssayExperiment, plotly, rmarkdown, spelling, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BatchQC_2.8.3.tar.gz
Windows Binary (x86_64) BatchQC_2.8.3.zip
macOS Binary (big-sur-x86_64) BatchQC_2.8.3.tgz
macOS Binary (sonoma-arm64) BatchQC_2.8.3.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/BatchQC
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/BatchQC
Package Short Url https://bioconductor.org/packages/BatchQC/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive