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simPIC

This is the development version of simPIC; for the stable release version, see simPIC.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19

Flexible simulation of paired-insertion counts for single-cell ATAC-sequencing data


Bioconductor version: Development (3.24)

simPIC is a package for simulating single-cell ATAC-seq count data. It provides a user-friendly, well documented interface for data simulation. Functions are provided for parameter estimation, realistic scATAC-seq data simulation, and comparing real and simulated datasets.

Author: Sagrika Chugh [aut, cre] ORCID iD ORCID: 0000-0002-8050-5214 , Heejung Shim [aut], Davis McCarthy [aut]

Maintainer: Sagrika Chugh <sagrika.chugh at gmail.com>

Citation (from within R, enter citation("simPIC")):

Sagrika Chugh, Heejung Shim, Davis McCarthy. simPIC: Flexible simulation of paired-insertion counts for single-cell ATAC-sequencing data. doi:10.18129/B9.bioc.simPIC, R package version 1.9.0, https://bioconductor.org/packages/simPIC.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("simPIC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("simPIC")
simPIC: simulating single-cell ATAC-seq data HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews ATACSeq, DataImport, ImmunoOncology, Sequencing, SingleCell, Software
Version1.9.0
In Bioconductor sinceBioC 3.19 (R-4.4) (2.5 years)
License GPL-3
Depends R (>= 4.5.0), SingleCellExperiment
Imports BiocGenerics, checkmate (>= 2.0.0), fitdistrplus, matrixStats, actuar, Matrix, stats, SummarizedExperiment, rlang, S4Vectors, GenomeInfoDb, methods, scales, scuttle, edgeR, withr
System Requirements
URLhttps://github.com/sagrikachugh/simPIC
Bug Reportshttps://github.com/sagrikachugh/simPIC/issues
See More
Suggests bluster, ggplot2 (>= 3.4.0), knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0), scater, scran, magick, splatter, VariantAnnotation, IRanges, GenomicRanges, preprocessCore
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package simPIC_1.9.0.tar.gz
Windows Binary (x86_64) simPIC_1.9.0.zip
macOS Binary (big-sur-x86_64) simPIC_1.9.0.tgz
macOS Binary (sonoma-arm64) simPIC_1.9.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/simPIC
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/simPIC
Package Short Url https://bioconductor.org/packages/simPIC/
Package Downloads ReportDownload Stats