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panoramic

This is the development version of panoramic; to use it, please install the devel version of Bioconductor.

Variance-Aware Multi-Sample Spatial Colocalization Analysis


Bioconductor version: Development (3.24)

Quantifies and compares cell-type spatial colocalization across samples, patients, and conditions in spatial omics studies. Its primary statistic, edge-corrected local competition enrichment, measures excess or deficit local mixing for ordered cell-type pairs on a percentage-point scale. The package estimates within-sample uncertainty with spatial bootstrap procedures and propagates it through multilevel random-effects meta-analysis for pooled inference and group-level contrasts; classical spatial summary statistics are also supported.

Author: Jacob Chang [aut, cre, fnd] ORCID iD ORCID: 0000-0002-3719-7949

Maintainer: Jacob Chang <jachang4 at stanford.edu>

Citation (from within R, enter citation("panoramic")):

Jacob Chang. panoramic: Variance-Aware Multi-Sample Spatial Colocalization Analysis. doi:10.18129/B9.bioc.panoramic, R package version 0.99.4, https://bioconductor.org/packages/panoramic.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("panoramic")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("panoramic")
PANORAMIC tutorial HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews SingleCell, Software, Spatial
Version0.99.4
In Bioconductor sinceBioC 3.24 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5)
Imports dplyr, ggplot2, ggrepel, igraph, tidygraph, ggraph, rlang, S4Vectors, SummarizedExperiment, spatstat.geom, spatstat.explore, BiocParallel, SpatialExperiment, concaveman, metafor, withr, matrixStats
System Requirements
URLhttps://github.com/plevritis-lab/panoramic
Bug Reportshttps://github.com/plevritis-lab/panoramic/issues
See More
Suggests knitr, markdown, rmarkdown, BiocStyle, testthat (>= 3.0.0)
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package panoramic_0.99.4.tar.gz
Windows Binary (x86_64) panoramic_0.99.4.zip
macOS Binary (big-sur-x86_64) panoramic_0.99.4.tgz
macOS Binary (sonoma-arm64) panoramic_0.99.4.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/panoramic
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/panoramic
Package Short Url https://bioconductor.org/packages/panoramic/
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