Bioconductor Developer Survey 2026 Now Open!

maaslin3

This is the development version of maaslin3; for the stable release version, see maaslin3.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21

"Refining and extending generalized multivariate linear models for meta-omic association discovery"


Bioconductor version: Development (3.24)

MaAsLin 3 refines and extends generalized multivariate linear models for meta-omicron association discovery. It finds abundance and prevalence associations between microbiome meta-omics features and complex metadata in population-scale epidemiological studies. The software includes multiple analysis methods (including support for multiple covariates, repeated measures, and ordered predictors), filtering, normalization, and transform options to customize analysis for your specific study.

Author: William Nickols [aut, cre] ORCID iD ORCID: 0000-0001-8214-9746 , Jacob Nearing [aut]

Maintainer: William Nickols <willnickols at g.harvard.edu>

Citation (from within R, enter citation("maaslin3")):

William Nickols, Jacob Nearing. maaslin3: "Refining and extending generalized multivariate linear models for meta-omic association discovery". doi:10.18129/B9.bioc.maaslin3, R package version 1.5.7, https://bioconductor.org/packages/maaslin3.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("maaslin3")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("maaslin3")
Manual HTML R Script
Tutorial HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Metagenomics, Microbiome, MultipleComparison, Normalization, Software
Version1.5.7
In Bioconductor sinceBioC 3.21 (R-4.5) (1.5 years)
License MIT + file LICENSE
Depends R (>= 4.4)
Imports data.table, collapse (>= 2.1.0), lmerTest, lme4, optparse, mirai, multcomp, ggplot2, RColorBrewer, patchwork, scales, rlang, ggnewscale, survival, methods, BiocGenerics, reformulas
System Requirements
URLhttp://huttenhower.sph.harvard.edu/maaslin3
Bug Reportshttps://github.com/biobakery/maaslin3/issues
See More
Suggests knitr, testthat (>= 2.1.0), rmarkdown, markdown, kableExtra, dplyr, SummarizedExperiment, TreeSummarizedExperiment
Linking To
Enhances
Depends On Me
Imports Me benchdamic, MMUPHin
Suggests Me dar, DAssemble, miaViz, OMA
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package maaslin3_1.5.7.tar.gz
Windows Binary (x86_64) maaslin3_1.5.7.zip
macOS Binary (big-sur-x86_64) maaslin3_1.5.7.tgz
macOS Binary (sonoma-arm64) maaslin3_1.5.7.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/maaslin3
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/maaslin3
Package Short Url https://bioconductor.org/packages/maaslin3/
Package Downloads ReportDownload Stats