fishash

Cell Hashing with One-Sided Fisher Test

Bioconductor version: 3.24 · Package version: 0.99.3

Assigns guide RNAs or other genetic perturbations to cells in single-cell sequencing experiments using a one-sided Fisher's exact test. Implements an iterative refitting procedure to mitigate Simpson's paradox, supports multiple false discovery rate correction methods (Benjamini-Hochberg, Benjamini-Yekutueli, and Guo & Sarkar 2020), and provides simulation utilities for benchmarking demultiplexing methods. Results are returned as SummarizedExperiment objects.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("fishash")