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MetaPathNet

KEGG-Based Metabolic and Signaling Network Analysis for Systems Biology

Bioconductor version: 3.24 · Package version: 0.99.5

Provides tools to construct KEGG-based metabolic and signaling networks as edge lists for single-organism or cross-species analyses. The package supports identifier mapping, shortest-path and topology analyses, community detection, permutation testing, pathway over-representation analysis, and node annotation for host-microbiome studies. It also provides network visualisation in R and Cytoscape and supports extension of KEGG-based networks through additional reaction resources and user-defined reactions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MetaPathNet")

Details

MaintainerZhaojie Wang <zhaojie.wang@cnrs.fr>
AuthorZhaojie Wang [aut, cre] (ORCID: <https://orcid.org/0009-0009-7191-2107>), Francesc Puig-Castellvi [aut], Manyi Jia [aut], Marc-Emmanuel Dumas [aut, ths], Centre National de la Recherche Scientifique [fnd], Imperial College London [fnd], French National Research Agency [fnd]
LicenseMIT + file LICENSE
URLhttps://github.com/zhaojie-wang/MetaPathNet
Bug Reportshttps://github.com/zhaojie-wang/MetaPathNet/issues
System RequirementsCytoscape (>= 3.9.0) for Cytoscape-based visualisation functions
Downloads rank33
Source branchdevel
biocViewsClassification, KEGG, Microbiome, Network, Pathways, Software, SystemsBiology

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageMetaPathNet_0.99.5.tar.gz
Windows binary (x86_64)MetaPathNet_0.99.5.zip
macOS binary (arm64)MetaPathNet_0.99.5.tgz
macOS binary (x86_64)MetaPathNet_0.99.5.tgz
Dependencies

Depends: R (>= 4.5.0)

Imports: igraph, httr, utils, RCurl, RCy3, tidygraph, ggraph, dplyr, KEGGREST, KEGGgraph, graph, mygene, ggplot2, rlang, curl, jsonlite, webchem, grDevices, grid, stats

Suggests: testthat, knitr, rmarkdown, BiocStyle