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VERSO

This is the development version of VERSO; for the stable release version, see VERSO.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12

Viral Evolution ReconStructiOn (VERSO)


Bioconductor version: Development (3.24)

Mutations that rapidly accumulate in viral genomes during a pandemic can be used to track the evolution of the virus and, accordingly, unravel the viral infection network. To this extent, sequencing samples of the virus can be employed to estimate models from genomic epidemiology and may serve, for instance, to estimate the proportion of undetected infected people by uncovering cryptic transmissions, as well as to predict likely trends in the number of infected, hospitalized, dead and recovered people. VERSO is an algorithmic framework that processes variants profiles from viral samples to produce phylogenetic models of viral evolution. The approach solves a Boolean Matrix Factorization problem with phylogenetic constraints, by maximizing a log-likelihood function. VERSO includes two separate and subsequent steps; in this package we provide an R implementation of VERSO STEP 1.

Author: Daniele Ramazzotti [aut] ORCID iD ORCID: 0000-0002-6087-2666 , Fabrizio Angaroni [aut], Davide Maspero [cre, aut], Alex Graudenzi [aut], Luca De Sano [aut] ORCID iD ORCID: 0000-0002-9618-3774

Maintainer: Davide Maspero <d.maspero at campus.unimib.it>

Citation (from within R, enter citation("VERSO")):

Daniele Ramazzotti, Fabrizio Angaroni, Davide Maspero, Alex Graudenzi, Luca De Sano. VERSO: Viral Evolution ReconStructiOn (VERSO). doi:10.18129/B9.bioc.VERSO, R package version 1.23.0, https://bioconductor.org/packages/VERSO.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("VERSO")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("VERSO")
Introduction HTML R Script
Running VERSO HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews BiomedicalInformatics, Sequencing, Software, SomaticMutation
Version1.23.0
In Bioconductor sinceBioC 3.12 (R-4.0) (6 years)
License file LICENSE
Depends R (>= 4.1.0)
Imports utils, data.tree, ape, parallel, Rfast, stats
System Requirements
URLhttps://github.com/BIMIB-DISCo/VERSO
Bug Reportshttps://github.com/BIMIB-DISCo/VERSO
See More
Suggests BiocGenerics, BiocStyle, testthat, knitr
Linking To
Enhances
Depends On Me
Imports Me
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Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package VERSO_1.23.0.tar.gz
Windows Binary (x86_64) VERSO_1.23.0.zip
macOS Binary (big-sur-x86_64) VERSO_1.23.0.tgz
macOS Binary (sonoma-arm64) VERSO_1.23.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/VERSO
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/VERSO
Package Short Url https://bioconductor.org/packages/VERSO/
Package Downloads ReportDownload Stats