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SVMDO

This is the development version of SVMDO; for the stable release version, see SVMDO.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17

Identification of Tumor-Discriminating mRNA Signatures via Support Vector Machines Supported by Disease Ontology


Bioconductor version: Development (3.24)

It is an easy-to-use GUI using disease information for detecting tumor/normal sample discriminating gene sets from differentially expressed genes. Our approach is based on an iterative algorithm filtering genes with disease ontology enrichment analysis and wilk and wilks lambda criterion connected to SVM classification model construction. Along with gene set extraction, SVMDO also provides individual prognostic marker detection. The algorithm is designed for FPKM and RPKM normalized RNA-Seq transcriptome datasets.

Author: Mustafa Erhan Ozer [aut, cre] ORCID iD ORCID: 0000-0002-1572-8008 , Pemra Ozbek Sarica [aut], Kazim Yalcin Arga [aut]

Maintainer: Mustafa Erhan Ozer <erhanozer19 at marun.edu.tr>

Citation (from within R, enter citation("SVMDO")):

Mustafa Erhan Ozer, Pemra Ozbek Sarica, Kazim Yalcin Arga. SVMDO: Identification of Tumor-Discriminating mRNA Signatures via Support Vector Machines Supported by Disease Ontology. doi:10.18129/B9.bioc.SVMDO, R package version 1.13.7, https://bioconductor.org/packages/SVMDO.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("SVMDO")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

No vignettes available
Reference ManualPDF

Details

biocViews Classification, DifferentialExpression, GUI, GeneSetEnrichment, RNASeq, Software, Survival, Transcriptomics
Version1.13.7
In Bioconductor sinceBioC 3.17 (R-4.3) (3.5 years)
License GPL-3
Depends R (>= 4.4), shiny (>= 1.7.4)
Imports shinyFiles (>= 0.9.3), shinytitle (>= 0.1.0), golem (>= 0.3.5), nortest (>= 1.0-4), e1071 (>= 1.7-12), BSDA (>= 1.2.1), data.table (>= 1.14.6), sjmisc (>= 2.8.9), klaR (>= 1.7-1), caTools (>= 1.18.2), caret (>= 6.0-93), survival (>= 3.4-0), DT (>= 0.33.0), DOSE (>= 3.24.2), AnnotationDbi (>= 1.60.0), org.Hs.eg.db (>= 3.16.0), dplyr (>= 1.0.10), SummarizedExperiment (>= 1.28.0), grDevices, graphics, stats, utils
System Requirements
URL
Bug Reportshttps://github.com/robogeno/SVMDO/issues
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Suggests BiocStyle, knitr, rmarkdown, testthat (>= 3.1.6)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) SVMDO_1.13.0.tgz
macOS Binary (sonoma-arm64) SVMDO_1.13.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/SVMDO
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/SVMDO
Package Short Url https://bioconductor.org/packages/SVMDO/
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