Test Changes in the Co-Localisation of Cell Types Between Groups of Patients


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Documentation for package ‘spicyR’ version 1.99.11

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bind The per-image values of every pair, as a data frame
buildKnnGraph Build a k-nearest-neighbour graph between cells
colTest Perform a simple wilcoxon-rank-sum test or t-test on the columns of a data frame
convPairs Converts colPairs object into an abundance matrix based on number of nearby interactions for every cell type.
diabetesData Imaging mass cytometry of human pancreas in type 1 diabetes (Damond et al. 2019)
getPairwise Get statistic from pairwise L curve of a single image.
getPairwiseProp Observed/expected proportion ratio for a fixed-k neighbourhood
getProp Get proportions from a SummarizedExperiment.
imageCrossPlot Pairwise cross-plot of spatial associations
plotImage Plot one image, showing the 'from' and 'to' cells of a pair
signifPlot Plots result of signifPlot.
spicy Test for changes in the co-localisation of cell types between conditions
spicyBoxPlot Box plot of one pair, with a point per image
SpicyResults The results of spicy()
SpicyResults-class The results of spicy()
spicyTest Results of the image-level test on diabetesData
topPairs A table of the significant results from spicy tests
topPairs-method A table of the significant results from spicy tests