.calc_IM_scores         Calculate interaction scores for a specific
                        pattern pair
.calc_threshold         Compute the threshold for identifying outlier
                        values or hotspots
.directed_SpaceMarkers
                        Directed SpaceMarkers workflow
.find_genes_of_interest
                        .find_genes_of_interest Identify genes
                        associated with pattern interaction. This
                        function identifies genes exhibiting
                        significantly higher values of testMat in the
                        Interaction region of the two patterns compared
                        to regions with exclusive influence from either
                        pattern. It uses Kruskal-Wallis test followed
                        by posthoc analysis using Dunn's Test to
                        identify the genes.
.pick_image             .pick_image
.row_t_test             Perform row-wise t-tests from scratch
.undirected_SpaceMarkers
                        Undirected SpaceMarkers workflow
SpaceMarkers            Main dispatcher for SpaceMarkers
SpaceMarkersExperiment
                        Create a SpaceMarkersExperiment object
SpaceMarkersExperiment-accessors
                        Accessor generics for SpaceMarkersExperiment
SpaceMarkersExperiment-class
                        SpaceMarkersExperiment class
add_features            Add spatial features to a
                        SpaceMarkersExperiment
analysis_type           Access or set the analysis type on a
                        SpaceMarkersExperiment
as-SingleCellExperiment-SpaceMarkersExperiment
                        Coercion from SingleCellExperiment to
                        SpaceMarkersExperiment
as-SpatialExperiment-SpaceMarkersExperiment
                        Coercion from SpatialExperiment to
                        SpaceMarkersExperiment
calculate_gene_scores_directed
                        Calculate interaction scores for all pattern
                        pairs
calculate_gene_set_score
                        calculate_gene_set_score
calculate_gene_set_specificity
                        calculate_gene_set_specificity
calculate_influence     Compute the spatial influence of a spatial
                        feature
calculate_lr_scores     calculate_lr_scores
calculate_overlap_directed
                        calculate_overlap_directed
calculate_overlap_undirected
                        calculate_overlap_undirected
calculate_thresholds    Compute the thresholds for all columns in a
                        data frame
create_lr_dataframe     Combine LR / ligand / receptor score matrices
                        into a long table
curated_genes           Curated Genes for example purposes
directed_scores         Access directed interaction scores on a
                        SpaceMarkersExperiment
find_all_hotspots       Find hotSpots for all spatial patterns
find_hotspots_gmm       Find hotspots for all patterns or influences
                        based on values
find_pattern_hotspots   Identify hotspots of spatial pattern influence
get_im_scores           get_im_scores
get_interacting_genes   Calculate Interaction Regions and Associated
                        Genes
get_pairwise_interacting_genes
                        get_pairwise_interacting_genes
get_spatial_features    Load spatial features
get_spatial_parameters
                        Read optimal parameters for spatial kernel
                        density from user input or .json file
get_spatial_params_morans_i
                        Calculate the optimal parameters from spatial
                        kernel density for cell-cell interactions
hotspots                Access hotspot assignments on a
                        SpaceMarkersExperiment
influence_map           Access the per-spot influence map on a
                        SpaceMarkersExperiment
interactions            Access pairwise interaction results on a
                        SpaceMarkersExperiment
load10X                 Load 10X Visium data as a
                        SpaceMarkersExperiment
load10XCoords           Load 10x Visium Spatial Coordinates
load10XExpr             Load 10X Visium Expression Data
load_anndata            Load an AnnData file as a
                        SpaceMarkersExperiment
lr_scores               Access ligand-receptor scores on a
                        SpaceMarkersExperiment
lrdf                    Curated Ligand-receptor interaction genes A
                        list of vectors with genes associated with
                        ligand-receptor interactions from CellChat
                        database
optParams               Optimal paramters of 5 patterns from CoGAPS.
overlap_map             Per-spot overlap classification map for a
                        pattern pair
overlap_scores          Access pattern overlap scores on a
                        SpaceMarkersExperiment
params                  Access analysis hyperparameters on a
                        SpaceMarkersExperiment
plot_cell_interaction_circos
                        Plot Ligand-Receptor Interactions between Cell
                        Types
plot_im_scores          plot_im_scores
plot_overlap_scores     plot_overlap_scores
plot_source_to_target_circos
                        Plot Ligand-Receptor Interactions from a Single
                        Source to Target Cell Types
plot_spatial            plot_spatial
plot_spatial_data_over_image
                        plotSpatialDataOverImage
plot_target_from_sources_circos
                        Plot Ligand-Receptor Interactions from Multiple
                        Source to a Single Target Cell Type
save_anndata            Save a SpaceMarkersExperiment as an AnnData
                        (.h5ad) file
spatial_params          Access or set the spatial-kernel parameters on
                        a SpaceMarkersExperiment
undirected_scores       Access undirected interaction scores on a
                        SpaceMarkersExperiment
