Rapid benchmarking of methods for *in silico* deconvolution of bulk RNA-seq data


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Documentation for package ‘granulator’ version 1.16.0

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benchmark Regress estimated cell type proportions against the ground truth
bulkRNAseq_ABIS PBMCs expression profiles (ABIS dataset)
correlate Pearson correlation of cell type proportions across cell types and methods
deconvolute Deconvolution from bulk RNAseq
get_decon_methods Deconvolution methods acronyms
get_TPM Convert raw counts to TPM
groundTruth_ABIS PBMCS true cell type proprotions (ABIS dataset)
load_ABIS Load demo PBMCs deconvolution data
plot_benchmark Plot benchmarking analysis scores
plot_correlate Plot of correlations between deconvolution methods
plot_deconvolute Estimated cell types across methods
plot_proportions Plot estimated cell type proportions
plot_regress Plot estimated cell type coefficients against the ground truth
plot_similarity Plot reference profile similariy matrix
sigMatrix_ABIS_S0 Signature matrix for deconvolution of PBMCs in 17 cell types
sigMatrix_ABIS_S1 Signature matrix for deconvolution of PBMCs in 13 cell types
sigMatrix_ABIS_S2 Signature matrix for deconvolution of PBMCs in 11 cell types
sigMatrix_ABIS_S3 Signature matrix for deconvolution of PBMCs in 9 cell types