Simulation and Deconvolution of Omic Profiles


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Documentation for package ‘deconvR’ version 1.13.0

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BSmeth2Probe A function to map WGBS methylation data to Illumina Probe IDs
deconvolute A function to deconvolute of bulk samples to their origin proportions using data from reference atlas (e.g. methylation signatures) Results of model are returned in dataframe "results". Summary of partial R-squared values of model (min, median, mean, max) are printed upon completion.
findSignatures A function to construct a signature matrix
HumanCellTypeMethAtlas The comprehensive human methylome reference atlas
IlluminaMethEpicB5ProbeIDs A dataset Illumina probe IDs of 400000 genomic loci (identified using the “seqnames”, “ranges”, and “strand” values).
simulateCellMix A function to generate a dataframe of mixed cell-type origin simulated samples using given reference atlas.